PI(5)P diC8 (Echelon Product Code: P-5008 100UG)
| Description: | Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8) is a synthetic, purified dioctanoyl PI(5)P. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4, 5)P2 by Type II PIP kinases. Alternate Names: Dioctanoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P C8, PI(5)P C8, or PI5P 1) Ikonomov, O. C., D. Sbrissa, et al. (2002). "Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3, 5-P2 production for endomembrane integrity." J Biol Chem 277(11): 9206-11. 2) Hinchliffe, K. A., M. L. Giudici, et al. (2002). "Type IIalpha phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms." Biochem J 363(Pt 3): 563-70. 3) Sbrissa, D., O. C. Ikonomov, et al. (2002). "Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells." J Biol Chem 277(49): 47276-84. |
| Order #: | ECH-P-5008-100UG |
| Unit Size: | 100 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice Or Gel Ice Depending On Destination |
| Storage: | -20 °C or below |
| Subcategory: | Lipids |
| More information: | Go to webpage |
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