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PI(5)P diC8 (ammonium salt) (Echelon Product Code: P-5008A 100UG)

PI(5)P diC8 (ammonium salt) (Echelon Product Code: P-5008A 100UG)
Description: Phosphatidylinositol 5-phosphate diC8 (ammonium salt) is a synthetic, purified dioctanoyl PI(5)P. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4, 5)P2 by Type II PIP kinases. Featured in Publications: 1) Ikonomov, O. C., D. Sbrissa, et al. (2002). "Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3, 5-P2 production for endomembrane integrity." J Biol Chem 277(11): 9206-11. 2) Hinchliffe, K. A., M. L. Giudici, et al. (2002). "Type IIalpha phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms." Biochem J 363(Pt 3): 563-70. 3) Sbrissa, D., O. C. Ikonomov, et al. (2002). "Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells." J Biol Chem 277(49): 47276-84. Alternate Names: Dipalmitoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P C8, PI(5)P C8, or PI5P
Order #: ECH-P-5008A-100UG
Unit Size: 100 ug
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: Dry Ice Or Gel Ice Depending On Destination
Storage: -20 °C or below
Subcategory: Lipids
More information: Go to webpage
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