S1P TAMRA (Echelon Product Code: S-200T 50UG)
| Description: | Sphingosine 1-phosphate (S1P) is a bioactive lysophospholipid formed by phosphorylation of sphingosine by sphingosine kinases. S1P binds to five G-protein coupled receptors designated S1P(1-5) leading to cell proliferation, motility, and has a role in regulation cell shape. In addition, S1P acts as an intracellular mediator in a receptor-independent manner regulating cell survival and Ca(2+) homeostasis. Sphingosine 1-phosphate TAMRA (S1P-TAMRA) is a S1P analog with natural erythro stereochemistry labeled at the terminus of the alkyl chain with tetramethylrhodamine. Excitation/Emission: 555/580 nm Featured in Publications 1) Kashem, M. A., et al. (2016). "A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay." u Assay Drug Dev Technol /u 14(1): 36-49. 2) Nagatake, T., et al. (2020). "Selective expression of claudin-5 in thymic endothelial cells regulates the blood"thymus barrier and T-cell export." u International Immunology /u 33(3): 171-182. 3) Pei, G., et al. (2021). "Cellular stress promotes NOD1/2-dependent inflammation via the endogenous metabolite sphingosine-1-phosphate." u The EMBO Journal /u : e106272. 4) Chahar, K. R., et al. (2021). "Sphingosine kinases negatively regulate the expression of matrix metalloproteases (MMP1 and MMP3) and their inhibitor TIMP3 genes via sphingosine 1-phosphate in extravillous trophoblasts." u Reproductive Medicine and Biology /u 20(3): 267-276. |
| Order #: | ECH-S-200T-50UG |
| Unit Size: | 50 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice Or Gel Ice Depending On Destination |
| Storage: | -20 °C or below |
| Subcategory: | Lipids |
| More information: | Go to webpage |
Add to request list
- Phone: +49 (0)89 3799666-6
- E-mail: info@biozol.de
MoBiTec is now part of BIOZOL
All orders and requests placed via the online shop on www.mobitec.com are processed by BIOZOL Diagnostica Vertrieb GmbH.
You will receive an order confirmation by fax or e-mail. More information regarding the ordering process can be found here.
Technical Service - Product Information
Viewed