S1P TAMRA (Echelon Product Code: S-200T 50UG)
| Description: | Sphingosine 1-phosphate (S1P) is a bioactive lysophospholipid formed by phosphorylation of sphingosine by sphingosine kinases. S1P binds to five G-protein coupled receptors designated S1P(1-5) leading to cell proliferation, motility, and has a role in regulation cell shape. In addition, S1P acts as an intracellular mediator in a receptor-independent manner regulating cell survival and Ca(2+) homeostasis. Sphingosine 1-phosphate TAMRA (S1P-TAMRA) is a S1P analog with natural erythro stereochemistry labeled at the terminus of the alkyl chain with tetramethylrhodamine. Excitation/Emission: 555/580 nm Featured in Publications 1) Kashem, M. A., et al. (2016). "A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay." u Assay Drug Dev Technol /u 14(1): 36-49. 2) Nagatake, T., et al. (2020). "Selective expression of claudin-5 in thymic endothelial cells regulates the blood"thymus barrier and T-cell export." u International Immunology /u 33(3): 171-182. 3) Pei, G., et al. (2021). "Cellular stress promotes NOD1/2-dependent inflammation via the endogenous metabolite sphingosine-1-phosphate." u The EMBO Journal /u : e106272. 4) Chahar, K. R., et al. (2021). "Sphingosine kinases negatively regulate the expression of matrix metalloproteases (MMP1 and MMP3) and their inhibitor TIMP3 genes via sphingosine 1-phosphate in extravillous trophoblasts." u Reproductive Medicine and Biology /u 20(3): 267-276. |
| Order #: | ECH-S-200T-50UG |
| Unit Size: | 50 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice Or Gel Ice Depending On Destination |
| Storage: | -20 °C or below |
| Subcategory: | Lipids |
| More information: | Go to webpage |
607.00 € *
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
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- Phone: +49 (0)89 3799666-6
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