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PLPro (UBPBio Product Code: V2120)

PLPro (UBPBio Product Code: V2120)
Description: Maturation of SARS-CoV-2 virus requires two proteases, 3C-like protease (3CLP) and Papain-like protease (PLP), to cleave the large polyproteins 1a and 1ab to generate functional proteins. which is essential for genome replication and Coronavirus virion production. Both proteases are encoded by the polyproteins. 3CLP is a cysteine protease and forms a homodimer. 3CLP is the drug target of PF-17321332, a main component of the oral anti-Covid-19 drug Paxlovid. PLP is also a cysteine protease that cleaves polyproteins and has deubiquitinating and deISG15ylating activities. PLP is also a potential anti-Covid-19 drug target. The recombinant SARS-CoV-2 papain-like protease contains the catalytic domain from Glu746 to Lys1060.
Order #: UBP-V2120-50
Unit Size: 50 µg
Supplier: UBPBio
Restrictions: Only available in selected countries.
Shipping: Dry ice
Storage: -80 °C
Subcategory: COVID-19 Research
More information: Go to webpage
Datasheet Flyer or Brochure Product Image
417.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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