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6xHis-Ube2F (UBPBio Product Code: C2100)

6xHis-Ube2F (UBPBio Product Code: C2100)
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Description: Ube2F is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for conjugation of Nedd8 to protein substrates. Neddylation is initiated by activating Nedd8 by the Nedd8 activating enzyme APPBP1/UBA3. Cullin is a well-known substrate for Neddylation. When NEDD8 is covalently bonded to the CRL, it stimulates its E3 Ub ligase activity. A new approach to cancer therapy involves hindering the Nedd8 conjugation pathway through inhibition of the NAE1/UBA3 enzyme.
Order #: UBP-C2100-25
Unit Size: 25 µg
Supplier: UBPBio
Restrictions: Only available in selected countries.
Shipping: Dry ice
Storage: -80 °C
Subcategory: E2 Conjugating Enzymes
More information: Go to webpage
Datasheet Flyer or Brochure Product Image
223.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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