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390 MMP FRET Substrate 11 - 5 mg

390 MMP FRET Substrate 11 - 5 mg
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Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense. This substrate is readily hydrolyzed by MMP-8, 9 and collagenase-3 (MMP-13), Abs/Em = 325/393 nm. The hydrolysis is inhibited in a 1:1 stoichiometric fashion by the tissue inhibitors of metalloproteinases, TIMP-1, TIMP-2, and TIMP-3.
Order #: ASP-AS-27109
Unit Size: 5 mg
Supplier: AnaSpec
Restrictions: Only available in Germany and selected European countries.
Shipping: RT
Storage: - 20 °C Darkness
Subcategory: Peptides
More information: Go to webpage
Datasheet Flyer or Brochure
562.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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