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Fibrinogen gamma-Chain (377-395) - 1 mg

Fibrinogen gamma-Chain (377-395) - 1 mg
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Description: Activation of the coagulation cascade converts fibrinogen to fibrin, through binding of an epitope in the fibrinogen γ chain (γ377–395) to CD11b/CD18 integrin (Mac-1). In the central nervous system, fibrinogen has been associated to demyelination and microglial activation, while this peptide attenuates microglia activation and suppresses relapsing paralysis in multiple sclerosis (MS). Since blocking fibrinogen–Mac-1 interactions affects the pro-inflammatory but not the pro-coagulant properties of fibrinogen, targeting this gamma-fibrinogen epitope could represent a potential therapeutic strategy for MS and other neuroinflammatory diseases associated with blood-brain barrier disruption and microglia activation.
Order #: ASP-AS-62128
Unit Size: 1 mg
Supplier: AnaSpec
Restrictions: Only available in Germany and selected European countries.
Shipping: RT
Storage: - 20 °C
Subcategory: Peptides
More information: Go to webpage
Datasheet Flyer or Brochure
185.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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