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[Asn23]-beta-Amyloid (1-40), Iowa Mutation - 0.5 mg

[Asn23]-beta-Amyloid (1-40), Iowa Mutation - 0.5 mg
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Description: Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA). The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.
Order #: ASP-AS-62145
Unit Size: 0.5 mg
Supplier: AnaSpec
Restrictions: Only available in Germany and selected European countries.
Shipping: RT
Storage: - 20 °C
Subcategory: Peptides
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