[Lys22]-beta-Amyloid (1-40), Italian Mutation - 0.5 mg
![[Lys22]-beta-Amyloid (1-40), Italian Mutation - 0.5 mg](https://www.mobitec.com/media/image/79/34/f6/Neuroscience_600x600.jpg)
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| Description: | Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. Among them, the Italian mutation (E22K) leads to beta-amyloid peptides which aggregate more rapidly and exhibit potent neurotoxicity compared to wild-type beta-amyloid 1-40. The formation of a salt bridge between Lys-22 and Asp-23 in the minor conformer might explain why E22K-beta-amyloid 1-40 is more pathogenic than its wild-type conterpart. |
| Order #: | ASP-AS-62147 |
| Unit Size: | 0.5 mg |
| Supplier: | AnaSpec |
| Restrictions: | Only available in Germany and selected European countries. |
| Shipping: | RT |
| Storage: | - 20 °C |
| Subcategory: | Peptides |
| More information: | Go to webpage |
351.00 € *
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
- Phone: +49 (0)89 3799666-6
- Fax: +49 (0)89 3799666-99
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- Phone: +49 (0)89 3799666-6
- E-mail: info@biozol.de
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