Description: | Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. Among them, the Tottori mutation produces beta amyloid peptides with the D7N substitution at the peptide N terminus. This was reported to accelerate the kinetics of oligomers formation which act as fibril seeds and are more toxic to cultured neuronal cells. |
Order #: | ASP-AS-63320 |
Unit Size: | 0.5 mg |
Supplier: | AnaSpec |
Restrictions: | Only available in Germany and selected European countries. |
Shipping: | RT |
Storage: | - 20 °C |
Subcategory: | Peptides |
More information: | Go to webpage |
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