[Lys(Me3)36]-Histone H3 (21-44)-GK(Biotin)

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Description:	This is a Histone 3 peptide trimethylated at lysine 36. It's role has been indicative of defining exons, as certain nucleosome-enriched exons are observed to be enriched in some histone modifications. It is belived that this pattern of modification as seen with this H3K36me3 peptide, influences alternative splicing, perhaps by signaling effector proteins to mark particular exons for inclusion in the final transcript as they exit the RNA Polymerase II complex. It has also been shown in yeast that H3K36me3 gets deposited on histones as they are displaced by RNA polymerase II (RNAPII) during transcription. H3K36me3 then serves as a mark for HDACs to bind and deacetylate the histones.
Order #:	ASP-AS-64441-1
Unit Size:	1 mg
Supplier:	AnaSpec
Restrictions:	Only available in Germany and selected European countries.
Shipping:	RT
Storage:	- 20 °C
Subcategory:	Peptides
More information:	Go to webpage

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522.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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