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Endothelin 3, cyclic (human, mouse, rabbit, rat) (Echelon Product Code: 335-10 0.5MG)

Endothelin 3, cyclic (human, mouse, rabbit, rat) (Echelon Product Code: 335-10 0.5MG)
Description: CAS Number: 117399-93-6 Molecular Weight: 2645.16 Salt Form: TFA Purity: 96% Sequence (3-letter): Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Cys1-Cys15, Cys3-Cys11) Sequence (1-letter): CTCFTYKDKECVYYCHLDIIW-OH Storage: -20 °C or below Solubility: water 1 mg/mL Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. Endothelin-3 is an endogenous neuropeptide and potent vasoconstrictor. Endothelin-3 has been reported to attenuate thrombin-evoked aggregation of human platelets, acts as a potent stimulator of interleukin-6 production by endothelial cell lines, activates phospholipase C in fibroblasts expressing ETA receptors and induces the production of VEGF. » References 1. Baynash, A.G. (1994) "Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons" Cell 79 (7): 1277"1285. 2. Matsumoto, H. et al. (1989) "Abundance of endothelin-3 in rat intestine, pituitary gland and brain" 164 (1): 74-80. 3. Sakamoto, A. et al. (1991) "Cloning and functional expression of human cDNA for the ETB endothelin receptor" Biochem. Biophys. Res. Commun. 178 (2): 656"663;
Order #: ECH-335-10-0.5MG
Unit Size: 0.5 mg
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: Room Temperature
Storage: -20 °C or below
Subcategory: Peptides
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