Gly-Arg-Gly-Asp-Ser (GRGDS) (Echelon Product Code: 450-38 5MG)
| Description: | CAS Number: 96426-21-0 Molecular Weight: 490.21 Salt Form: TFA Purity: 96% Sequence (3-letter): Gly-Arg-Gly-Asp-Ser-OH Sequence (1-letter): GRGDS-OH Storage: -20 °C or below Solubility: water or 5% acetic acid GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin. Osteopontin uses this motif for cell adhesion. This peptide includes the RGD (Arg-Gly-Asp) sequence found in many extracellular matrix adhesive proteins. GRGDS is a synthetic antagonist of integrin function and competitively inhibits direct fibroblast binding to fibronectin. » References 1.Miyamoto, S., Akiyama, S.A. and Yamada, K.M. (1995) "Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function" Science 267 (5199): 883-885. 2. Denhardt, D.T. and Guo, X. (1993) "Osteopontin: a protein with diverse functions" FASEB J. 7: 1475-1482. |
| Order #: | ECH-450-38-5MG |
| Unit Size: | 5 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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