Neuropeptide Y (human, rat) (Echelon Product Code: 611-26 1MG)
| Description: | CAS Number: 90880-35-6 Molecular Weight: 4271.76 Salt Form: TFA Purity: 96% Sequence (3-letter): Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2 Sequence (1-letter): YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2 Storage: -20 °C or below Solubility: water 1 mg/mL Neuropeptide Y (NPY) is a peptide that is abundant in the central and peripheral nervous system that plays a major role in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. NPY is a vasonconstrictor that inhibits Ca2+-activated K+ channels in vascular smooth muscle. Inhibition of NPY synthesis regulates food intake and metabolism implicating a role in obesity. This NPY amino acid sequence is homologous for human, rat, rabbit, and guinea pig. » References 1. Tatemoto, K., Carlquist, M. and Mutt, V. (1982) "Neuropeptide Y-a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide" Nature 296: 659-660. 2. a Stephens, T.W. et al. (2002) "The role of neuropeptide Y in the antiobesity action of the obese gene product" Nature 377: 530-532; 3.O"Barr, S. and Cooper, N.R. (2000) "The C5a complement activation peptide increases IL-1" and IL-6 release from amyloid-" primed human monocytes: implications for Alzheimer"s disease" J. Neuroimmunol. 109: 87"94. |
| Order #: | ECH-611-26-1MG |
| Unit Size: | 1 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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