Description: | CAS Number: 58889-67-1Molecular Weight: 1671.9Salt Form: TFAPurity: >96%Sequence (3-letter): Glp-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH (Glp = Pyroglutamic acid)Sequence (1-letter): (Glp)LYENKPRRPYIL-OHStorage: -20 °C or belowSolubility: water (0.7 mg/mL)Neurotensin (NT) is a brain and gastrointestinal peptide with many central and peripheral functions. It is a neurotransmitter-like hypothalamic peptide that lowers blood pressure increases vascular permeability and increases blood levels of glucagon glucose growth hormone and prolactin in rats. NT acts as modulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Peripherally NT acts as a paracrine and endocrine modulator of the digestive tract and cardiovascular systemReferences1. Carraway R. and Leeman S.E. (1973) “The Isolation of a New Hypotensive Peptide Neurotensin from Bovine Hypothalami†J. Biol. Chem. 248: 6854-6861.2. White J.F. et al. (2012) “Structure of the agonist-bound neurotensin receptor†Nature 490 (7421): 508-513.3. Tanaka K. Masu M. and Nakanishi S. (1990) “Structure and functional expression of the cloned rat neurotensin receptor†Neuron 4 (6 ): 847–854. |
Order #: | ECH-631-27-5MG |
Unit Size: | 5 mg |
Supplier: | Echelon Biosciences |
Restrictions: | Available in all European countries, except France & Italy. |
Shipping: | Room Temperature |
Storage: | -20 °C or below |
Subcategory: | Peptides |
More information: | Go to webpage |
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