a-Secretase Substrate (Echelon Product Code: 640-55 5MG)
| Description: | Molecular Weight: 2116.1 Salt Form: TFA Purity: 96% Sequence (3-letter): Ac-Arg-Glu(EDANS)-Val-His-His-Gln-Lys-Leu-Val-Phe-Lys(Dabcyl)-Arg-OH Sequence (1-letter): Ac-RE(EDANS)VHHQKLVFK(Dabcyl)R-OH Storage: -20 °C or below a-Secretase Substrate is an internally quenched fluorogenic peptide containing the "-secretase cleavage site of "-Amyloid Precursor Protein (APP). Cleavage occurs at the Lys-Leu bond and fluorescence can be measured at 490 nm. Komano H, Seeger M, Gandy S, Wang GT, Krafft GA, Fuller RS. Involvement of cell surface glycosyl-phosphatidylinositol-linked aspartyl proteases in alpha-secretase-type cleavage and ectodomain solubilization of human Alzheimer beta-amyloid precursor protein in yeast. J Biol Chem. 1998 Nov 27;273(48):31648-51. doi: 10.1074/jbc.273.48.31648. PMID: 9822624; |
| Order #: | ECH-640-55-5MG |
| Unit Size: | 5 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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