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ADAM substrate (Echelon Product Code: 825-15 5MG)

ADAM substrate (Echelon Product Code: 825-15 5MG)
Description: CAS Number: 1926163-42-9 Molecular Weight: 1760.93 Salt Form: TFA Purity: 96% Sequence (3-letter): H-Glu(EDANS)-Lys-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys(Dabcyl)-NH2 Sequence (1-letter): (Glu(EDANS))KPAKFFRL(Lys(Dabcyl))-NH2 Storage: -20 °C or below ADAM substrate is a FRET based fluorogenic substrate for ADAM metalloproteinases. The substrate contains the acceptor DABCYL, which acts as an acceptor for the donor, EDANS. Activity is quantified by release of fluorescent EDANS which excites at 365 nm and emits at 490 nm. ADAMs cleave extracellular portions of transmembrane proteins such as HER2 which is subsequently activated. Some ADAMS are also known as sheddases.
Order #: ECH-825-15-5MG
Unit Size: 5 mg
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: Room Temperature
Storage: -20 °C or below
Subcategory: Peptides
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