Ac-Tyr-Val-Ala-Asp-AFC (Caspase 1 (ICE) Substrate) (Echelon Product Code: 860-17 25MG)
| Description: | CAS Number: 219137-85-6 Molecular Weight: 719.24 Salt Form: N/A Purity: 96% Sequence (3-letter): Ac-Tyr-Val-Ala-Asp-AFC Sequence (1-letter): Ac-YVAD-AFC Storage: -20 °C or below Solubility: DMSO, 10 mg/mL Ac-YVAD-AFC is a fluorogenic substrate for caspase-1 and caspase-4. Reactions are monitored by measuring an increase in fluorescence signal due to AFC cleavage. The excitation and emission maxima for AFC are 400 nm and 505 nm, respectively. » References 1. Deveraux, Q.L. et al. (1997) "X-linked IAP is a direct inhibitor of cell-death proteases" Nature 388: 300-304. 2. Wang, X. et al. (2003) µMinocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease" Proc. Natl. Acad. Sci. USA 100 (18): 10483"10487. |
| Order #: | ECH-860-17-25MG |
| Unit Size: | 25 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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