Description: | CAS Number: 189684-54-6 Molecular Weight: 636.28 Salt Form: N/A Purity: 96% Sequence (3-letter): Ac-Val-Glu-Ile-Asp-pNA Sequence (1-letter): Ac-VEID-pNA Storage: -20 °C or below Ac-Val-Glu-Ile-Asp-pNA is a colorimetric substrate for Caspase 6. Caspase 6 (Mch2) is a cysteine protease involved in the execution phase of apoptosis, mediating neuronal shrinkage. In addition, it has important roles in neurodegenerative disorders such as Huntington"s, Parkinson"s, and Alzheimer"s diseases. Caspase 6 cleaves the mutated huntintin protein and the amyloid precursor protein resulting in the aggregating protein fragments typical of Huntington"s and Alzheimer"s diseases respectively. Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm. |
Order #: | ECH-860-50-25MG |
Unit Size: | 25 mg |
Supplier: | Echelon Biosciences |
Restrictions: | Available in all European countries, except France & Italy. |
Shipping: | Room Temperature |
Storage: | -20 °C or below |
Subcategory: | Peptides |
More information: | Go to webpage |
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