Ac-Val-Gln-Val-Asp-pNA (Caspase 3 Substrate) (Echelon Product Code: 860-54 25MG)
| Description: | Molecular Weight: 621.28 Salt Form: N/A Purity: 96% Sequence (3-letter): Ac-Val-Gln-Val-Asp-pNA Sequence (1-letter): Ac-VQVD-pNA Storage: -20 °C or below Ac-Val-Gln-Val-Asp-pNA is a colorimetric Caspase 3 substrate. Caspase 3 is a cysteine protease that is rapidly activated during apoptosis and that cleaves several substrates, including poly(ADP-ribose) polymerase (PARP). Caspase 3 is activated by Caspases 8, 9 and 10 and cleaves and activates caspase 6 and 7. Caspase 3 cleaves the amyloid precursor protein (APP) contributing to Amyloid beta formation and has been implicated in Alzheimer"s disease and proposed as a target for drug discovery. Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm. |
| Order #: | ECH-860-54-25MG |
| Unit Size: | 25 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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