TACE Substrate (Fluorogenic) (Echelon Product Code: 860-78 1MG)
| Description: | CAS Number: 396716-14-6 Molecular Weight: 1572.76 Salt Form: TFA Purity: 95% Sequence (3-letter): Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS Sequence (1-letter): Dabcyl-LAQAVRSSSR-EDANS Storage: -20 °C or below Dabcyl-LAQAVRSSSR-EDANS is a fluorescence energy transfer (FRET) peptide substrate for tumor necrosis factor (TNF)-" convertase (TACE) (Km ~19 µM). TACE, also known as ADAM 17, cleaves TNF-" from the membrane to activate it. TACE cleaves the Ala-Val bond and the substrate can be used to screen for inhibitors. Activity is quantified by release of fluorescent EDANS which excites at 365 nm and emits at 490 nm. |
| Order #: | ECH-860-78-1MG |
| Unit Size: | 1 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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