Ac-YVAD-CHO, Caspase 1 (ICE) Inhibitor (Echelon Product Code: 864-15 5MG)
| Description: | CAS Number: 143313-51-3 Molecular Weight: 492.22 Salt Form: N/A Purity: 95% Sequence (3-letter): Ac-Tyr-Val-Ala-Asp-CHO Sequence (1-letter): Ac-YVAD-CHO Storage: -20 °C or below Solubility: DMSO (5 mg/ml), water (5 mg/ml), ethanol (30 mg/ml), DMF (30 mg/ml) N-Ac-Tyr-Val-Ala-Asp-CHO (Ac-YVAD-CHO) is a synthetic peptide that reversibly and selectively inhibits interleukin-1" converting enzyme (ICE; Caspase-1). Caspase-1 is a pro-inflammatory cytokine and like other caspase inhibitors, interferes with the initiation of apoptosis and has numerous possible clinical applications » References 1. Cerretti D.P., et al. (1992) µMolecular cloning of the interleukin-1 beta converting enzyme" Science 256: 97"100. 2.Thornberry N.A. et al. (1992) "A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes" Nature 356: 768"774. |
| Order #: | ECH-864-15-5MG |
| Unit Size: | 5 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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