Ac-DEVD-CHO, Caspase 3 (Apopain) Inhibitor (Echelon Product Code: 864-20 5MG)
| Description: | CAS Number: 184179-08-6 Molecular Weight: 502.19 Salt Form: N/A Purity: 95% Sequence (3-letter): Ac-Asp-Glu-Val-Asp-CHO Sequence (1-letter): Ac-DEVD-CHO Storage: -20 °C or below Solubility: 13.7 mg/ml in DMSO Caspase-3 (Apopain) is commonly activated by numerous death signals and cleaves a variety of important cellular proteins and is essential for brain development. Ac-DEVD-CHO is a potent, reversible inhibitor of caspase-3 (Ki 1nM for purified caspase-3) and also inhibits caspase-7 (Ki = 1.6 nM) as well as other caspases to a lesser extent. » References 1. Talanian, R.V. et al (1997) "Substrate Specificities of Caspase Family Proteases" 272 (15): 9677"9682. 2. Godinat, A. et al. (2013) "A Biocompatible in Vivo Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Mice" ACS Chemical Biology 8 (5): 987-999. |
| Order #: | ECH-864-20-5MG |
| Unit Size: | 5 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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