Description: | CAS Number: 167498-29-5 Molecular Weight: 446.18 Salt Form: N/A Purity: 95% Sequence (3-letter): Z-Phe-Tyr-CHO Sequence (1-letter): Z-FY-CHO Storage: -20 °C or below Z-Phe-Tyr-CHO is a reversible peptidyl aldehyde inhibitor of Cathepsin L (IC(50)=0.85 nM). It is selective vs cathepsin B and calpain II (IC(50)s=85.1 and 184 nM respectively). Cathepsin L is a lysosomal cysteine protease with an important role in initiating protein degradation. Cathepsin L is also upregulated in several cancers and has been suggested as a drug target. In addition, extracellular secretion of Cathepsin L by tumors implicates it as a potential serum biomarker for cancer progression. |
Order #: | ECH-866-28-5MG |
Unit Size: | 5 mg |
Supplier: | Echelon Biosciences |
Restrictions: | Available in all European countries, except France & Italy. |
Shipping: | Room Temperature |
Storage: | -20 °C or below |
Subcategory: | Peptides |
More information: | Go to webpage |
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