Z-Phe-Arg-AFC (Cathepsin L Substrate) (Echelon Product Code: 866-75 10MG)
| Description: | CAS Number: 65147-22-0 Molecular Weight: 666.24 Salt Form: TFA Purity: 96% Sequence (3-letter): Z-Phe-Arg-AFC Sequence (1-letter): Z-FR-AFC Storage: -20 °C or below Z-Phe-Arg-AFC is a fluorogenic for Cathepsin L. Cathepsin L is a lysosomal cysteine protease with an important role in initiating protein degradation. Cathepsin L is also upregulated in several cancers and has been suggested as a drug target. In addition, extracellular secretion of Cathepsin L by tumors implicates it as a potential serum biomarker for cancer progression. Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm. |
| Order #: | ECH-866-75-10MG |
| Unit Size: | 10 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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