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PKC Isoenzyme Inhibitor (myristoylated) (Echelon Product Code: 880-17 1MG)

PKC Isoenzyme Inhibitor (myristoylated) (Echelon Product Code: 880-17 1MG)
Description: Molecular Weight: 880.17 Salt Form: TFA Purity: 95% Sequence (3-letter): N-Myr-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH Sequence (1-letter): (Myristoyl)EAVSLKPT-OH Storage: -20 °C or below Protein kinase C epsilon, PKC(e), is involved in the regulation of diverse cellular functions including neurotransmitter release in the brain. Translocation of PKC(e) is a marker of activity and can be blocked with isozyme specific peptides. This peptide is the myristoylated version of an octapeptide PKC(e) inhibitor (Cat# 880-15;). Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH is a selective inhibitor of the translocation of PKC(e). It can be used to resolve the functions of PKC(e) from those of other PKC isozymes. » References Obis(et al.) (2015) The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release. Molecular Brain (8)
Order #: ECH-880-17-1MG
Unit Size: 1 mg
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: Room Temperature
Storage: -20 °C or below
Subcategory: Peptides
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