Bz-Arg-Gly-Phe-Phe-Pro-4MbNA (Cathepsin D Substrate) (Echelon Product Code: 880-42 1MG)
| Description: | Molecular Weight: 881.42 Salt Form: HCl Purity: 96% Sequence (3-letter): Bz-Arg-Gly-Phe-Phe-Pro-4MbNA Sequence (1-letter): Bz-RGFFP-4MbNA Storage: -20 °C or below Bz-Arg-Gly-Phe-Phe-Pro-4MbNA is a fluorogenic substrate for Cathepsin D. Cathepsin D is a lysosomal aspartyl protease whose role is to degrade and activate intracellular proteins including hormones, enzyme precursors, and growth factors. Over expression in tumors stimulates metastasis and considered a marker of poor prognosis in breast cancer. Activity is quantified by release of free fluorescent 4-Methoxy-"-naphthylamine (4M"NA) which excites at 335-350 nm and emits at 410-440 nm. |
| Order #: | ECH-880-42-1MG |
| Unit Size: | 1 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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