MG-115 (Proteasome Inhibitor) (Echelon Product Code: 882-10 5MG)
| Description: | CAS Number: 133407-86-0 Molecular Weight: 461.29 Salt Form: N/A Purity: 96% Sequence (3-letter): Z-Leu-Leu-Nva-CHO Sequence (1-letter): Z-LL(Nva)-CHO Storage: -20 °C or below MG-115 (Z-Leu-Leu-Nva-CHO) is a potent, cell permeable inhibitor of the 20S proteosome. It forms a reversible hemiacetal adduct and can also inhibit cathepsins and calpains. It reduces degradation of ubiquitinated proteins and blocks proteolytic conversion of protein precursors. MG-115 is known to induce the heat shock response and apoptosis. » References Rock, K.L., Gramm, C., Rothstein, L., et al. (1994) "Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules". Cell78, 761-771. |
| Order #: | ECH-882-10-5MG |
| Unit Size: | 5 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Peptides |
| More information: | Go to webpage |
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