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Autocamtide-2 Related Inhibitory Peptide, myristoylated (Echelon Product Code: 891-26 5MG)

Autocamtide-2 Related Inhibitory Peptide, myristoylated (Echelon Product Code: 891-26 5MG)
Description: Molecular Weight: 1707.08 Salt Form: TFA Purity: 96% Sequence (3-letter): Myristoyl-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH Sequence (1-letter): (Myristoyl)KKALRRQEAVDAL-OH Storage: -20 °C or below Autocamtide-2 Related Inhibitory Peptide is a calmodulin-dependent protein kinase II (CaMKII) inhibitor (IC(50) = 40 nM) that contains the autophosphorylation site (Thr(286)/Thr(287)) found within the autoinhibitory domain of the protein kinase. It is nonphosphorylatable and selective for CaMKII over other protein kinases such as PKC and PKA and is not capable of being phosphorylated. This compound is a used to study the physiological roles of CaMKII. The myristoyl modification allows for cell permeability. » References Ishida, A., Kameshita, I., Okuno, S., et al. (1995) "A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II".Biochemical and Biophysical Research Communications212(3), 806-812;
Order #: ECH-891-26-5MG
Unit Size: 5 mg
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: Room Temperature
Storage: -20 °C or below
Subcategory: Peptides
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