Description: | LDN-57444 is a potent small chemical inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1, IC50 = 0.88 μM). UCHL1 functions to generate free ubiquitin from ubiquitin precursors. Loss of UCH-L1 activity causes apoptosis due to an impaired ubiquitin-proteasome pathway. LDN-57444-induced reduction of free ubiquitin could increase spine size while decreasing spine density in hippocampal neurons. |
Order #: | UBP-F2104-25-25 |
Unit Size: | 25 mg |
Supplier: | UBPBio |
Restrictions: | Only available in selected countries. |
Shipping: | Ambient temp. |
Storage: | -20 °C |
Subcategory: | Proteasome / Deubiquitinase Inhibitors |
More information: | Go to webpage |
402.00 € *
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
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