LDN-57444 (UBPBio Product Code: F2104-25)
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| Description: | LDN-57444 is a potent small chemical inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1, IC50 = 0.88 μM). UCHL1 functions to generate free ubiquitin from ubiquitin precursors. Loss of UCH-L1 activity causes apoptosis due to an impaired ubiquitin-proteasome pathway. LDN-57444-induced reduction of free ubiquitin could increase spine size while decreasing spine density in hippocampal neurons. |
| Order #: | UBP-F2104-25-25 |
| Unit Size: | 25 mg |
| Supplier: | UBPBio |
| Restrictions: | Only available in selected countries. |
| Shipping: | Ambient temp. |
| Storage: | -20 °C |
| Subcategory: | Proteasome / Deubiquitinase Inhibitors |
| More information: | Go to webpage |
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