Description: | Necrostatin-1 is a potent inhibitor of necroptosis, a programmed and caspase-independent cell death mechanism. The death domain receptor-associated serine/threonine kinase RIP1 is essential for TNF-induced necrosis. Necrostatin-1 inhibits RIP1 and blocks TNFα-induced necrosis of FADD-deficient Jurkat cells with an EC50 value of 490 nM. |
Order #: | UBP-F7101-25 |
Unit Size: | 25 mg |
Supplier: | UBPBio |
Restrictions: | Only available in selected countries. |
Shipping: | Ambient temp. |
Storage: | -20 °C |
Subcategory: | Proteasome / Deubiquitinase Inhibitors |
More information: | Go to webpage |
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