Description: | S5a is one of the integral Ub receptors of the 26S proteasome. It’s N-terminal vWA domain interacts with Rpn9 and Rpn10 on the 26S proteasome. The C-terminal domain of S5a contains two Ub-interacting motifs (UIMs) that bind Ub and Ub chains. S5a prefers to bind polyUb chains; it also binds proteins containing a Ub-like domain. It may directly recognize ubiquitinated proteins or coordinate with other Ub receptors to target substrates for proteasomal degradation. |
Order #: | UBP-A3300-25 |
Unit Size: | 25 µg |
Supplier: | UBPBio |
Restrictions: | Only available in selected countries. |
Shipping: | Dry ice |
Storage: | -80 °C |
Subcategory: | Proteasomes / Activators / Subunits |
More information: | Go to webpage |
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