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Human Sirtuin 2, recombinant

Human Sirtuin 2, recombinant
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Description: Histone deacetylases (HDACs) act as transcriptional repressors of genes catalyzing the removal of acetyl groups from a ε-N-acetyl lysine of histone. Sirtuin 2 (SIRT2) belongs to a unique class of nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases (class III HDACs) that target multiple protein substrates to execute diverse biological functions. Sirtuin 2 is the member of the family of Sir2 (Silent Information Regulator 2) proteins. Besides histones, substrates for SIRT2 also include various transcription factors, the tumor suppressor p53 and alpha-tubulin. Human SIRT2 is a cytoplasmic protein that increases in abundance during mitosis and regulates major events of cytokinesis.
Order #: ASP-AS-72187
Unit Size: 10 µg
Supplier: AnaSpec
Restrictions: Only available in Germany and selected European countries.
Shipping: Dry Ice
Storage: - 78 °C
Subcategory: Proteins
More information: Go to webpage
Datasheet Flyer or Brochure
218.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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