Human Sirtuin 2, recombinant
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| Description: | Histone deacetylases (HDACs) act as transcriptional repressors of genes catalyzing the removal of acetyl groups from a ε-N-acetyl lysine of histone. Sirtuin 2 (SIRT2) belongs to a unique class of nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases (class III HDACs) that target multiple protein substrates to execute diverse biological functions. Sirtuin 2 is the member of the family of Sir2 (Silent Information Regulator 2) proteins. Besides histones, substrates for SIRT2 also include various transcription factors, the tumor suppressor p53 and alpha-tubulin. Human SIRT2 is a cytoplasmic protein that increases in abundance during mitosis and regulates major events of cytokinesis. |
| Order #: | ASP-AS-72187 |
| Unit Size: | 10 µg |
| Supplier: | AnaSpec |
| Restrictions: | Only available in Germany and selected European countries. |
| Shipping: | Dry Ice |
| Storage: | - 78 °C |
| Subcategory: | Proteins |
| More information: | Go to webpage |
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