Description: | NF-κB essential modulator (NEMO) is a regulatory subunit within IκB kinase (IKK). IKK is also composed of two unrelated catalytic subunits called IKKα and IKKβ. NEMO is additionally referred to as IKKγ, IKKAP1, or FIP-3. IKK is responsible for activating the transcription factor, NF-κB, which is involved in immune response. NEMO prefers to bind K63-linked or linear polyubiquitin chains. The L329P substitution abolishes NEMO interacts with linear polyUb chains and long K63 polyubiquitin chains. |
Order #: | UBP-I1511-100 |
Unit Size: | 100 µg |
Supplier: | UBPBio |
Restrictions: | Only available in selected countries. |
Shipping: | Dry ice |
Storage: | -80 °C |
Subcategory: | Ubiquitin Binding Proteins |
More information: | Go to webpage |
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