6xHis-Nedd8 (UBPBio Product Code: E4100)
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| Description: | Nedd8 is an 81 amino acid Ub-like protein. It is conjugated to protein substrates in much the same way as Ub, using the E1, E2, E3 cascade. The specific E1 used is a heterodimer of APPBP1/UBA3. Two E2s have been discovered to follow called Ubc12 and Ube2F. Neddylation causes conformational change of the Cullin protein in the E3 called cullin-RING ligases (CRLs), which enhances the E3 Ub ligase activity of CRLs. |
| Order #: | UBP-E4100-500 |
| Unit Size: | 500 µg |
| Supplier: | UBPBio |
| Restrictions: | Only available in selected countries. |
| Shipping: | Dry ice |
| Storage: | -80 °C |
| Subcategory: | Ubiquitin / Ubiquitin-like Proteins / Mutants |
| More information: | Go to webpage |
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